Vantage Hemp is an American cannabidiol manufacturer based in Greeley, Colorado. Our custom-built pharmaceutical grade extraction and cannabidiol manufacturing facilities, named Falcon and Raven, deliver 62,000 sq ft of cGMP certified hemp processing. At Vantage Hemp, we understand the regulatory process for cannabidiol API registration, Investigational New Drug listings, clinical trial execution, and drug commercialization. With two Drug Master Files registered at the FDA, PIC/S certification from the Therapeutic Goods Administration of Australia. and ICH Q7, WHO GMP, and FDA 21 CFR 210/211 certification from SGS, our extraction and manufacturing facilities are designed to be compliant with all global pharmaceutical standards.
Pharmaceutical Grade Cannabidiol and Cannabigerol Manufacturing for Global Markets
Vantage Hemp Receives CBPF Protocol Number
The CBPF certification is a mandatory requirement for companies aiming to manufacture and distribute pharmaceutical products within Brazil, ensuring adherence to Good Manufacturing Practices (GMP) as stipulated by ANVISA. Working with a Brazilian partner, US-based cannabidiol manufacturer Vantage Hemp has completed its submission of the CBPF protocol and awaits final inspection.
US Cannabidiol Manufacturer Certified PIC/S by the TGA of Australia
Vantage Hemp, a pharmaceutical grade cannabidiol manufacturer, is proud to announce its achievement of PIC/S certification from Australia’s TGA for its botanically-sourced T-Free CBD Distillate API, CBD Isolate API, and finished goods. The PIC/S standard is recognized globally and opens markets both internally, and internationally.
European Pharmacopoeia Compliant CBD Isolate
Vantage Hemp’s Certificate of Analysis (CoA) for EP cGMP CBD Isolate (Batch: VH240043) demonstrates the cannabidiol manufacturer’s full alignment with the newly adopted European Pharmacopoeia monograph 07/2024:3151 for Cannabidiol (CBD).
Announcing Pharmaceutical Grade CBG Isolate
CBG, often referred to as the “mother cannabinoid,” is the precursor from which other cannabinoids, such as THC, CBD, and CBN, are derived. Unlike THC, CBG is non-psychoactive, meaning it does not produce the “high” commonly associated with cannabis use. This makes CBG a more attractive option for pharmaceutical applications.
Leading White Label Cannabidiol Manufacturing Services
Vantage Hemp provides top-quality white label and contract cannabidiol manufacturing services. We offer a wide range of safe, tested, and compliant pharmaceutical grade CBD products that are ready for retail branding and distribution. Have a custom formulation? Our team of expert formulation scientists can design scalable manufacturing processes for any product.
Cannabidiol Manufacturer – Product Guide 2025
Download Vantage Hemp’s Product Guide 2025 for a complete list of pharmaceutical grade CBD APIs and finished goods.
Cannabidiol Manufacturer – Compliance Package 2025
Download Vantage Hemp’s Compliance Package 2025 for a complete list of all of our certifications.
Raven Facility
Vantage’s Raven facility is home to the most advanced CBD extraction and processing capabilities, including hydrocarbon extraction, winterization, distillation, and crystallization.
- Receives CO2 extracted crude oil from Falcon
- Four state-of-the-art hydrocarbon extraction units capable of processing a total of four tons of biomass per day
- Winterization converting crude oil into refined FSO
- Distillation, using Chemtech KD30-dual-stage system, allows Raven to produce over 100,000 kg of CBD distillate annually
- Crystallization system capable of producing over 50,000 kg of isolate annually
Hydrocarbon Extraction
Vantage’s Raven facility houses four state of the art hydrocarbon extraction units that are the largest propane-based extraction units on the market today. Propane was selected because it minimizes extraction of byproducts, results in high CBD content in the crude and low post extraction processing requirements.
Vantage estimates that these units can process a combined 4 tons of biomass per day.
Winterization
Crude oil produced from either CO2 extraction or hydrocarbon extraction is winterized in the Raven facility to become purified full spectrum oil (“FSO”). Raw oil is dissolved in methanol, cooled down to a low temperature and filtered to remove fats, lipids and waxes.
The filtered methanol solution is then put through a falling film evaporator to remove methanol and collect the full spectrum oil. The oil is then heated under vacuum to remove any residual solvents, leaving behind a high-quality full spectrum oil with approximately 60-70% CBD content.
Distillation
Using a state-of-the-art Chemtech KD30 dual stage distillation system, Vantage can produce over 100,000kg of CBD distillate per year with a CBD content of 80 – 90%.
Isolation
Vantage has the capability to process distillate further using crystallization to produce CBD isolate with greater than 99.0% CBD purity. Vantage can produce approximately 50,000kg of CBD isolate each year.
Storage
The Raven facility contains a secure storage area for finished goods from which product is staged and shipped to end customers
Falcon Facility
Pre-Processing and Storage
- Raw unprocessed biomass enters the facility, and each bag is tested for potency and cannabinoid profile, as well as for pesticides, mycotoxins and heavy metals to ensure a high-quality end product
- For Super critical CO2 extraction, the biomass is decarboxylated prior to extraction which cuts total extraction time in half, significantly improving the efficiency of the process
- Decarboxylation involves the heating of biomass to 350oF, converting CBDa to CBD. To avoid oxidation, a nitrogen atmosphere is used to avoid degradation of the cannabinoids
- The Falcon building currently has capacity to hold 1,000,000 lbs. of biomass which is approximately 3 – 4 months worth of raw input at capacity
CO2 Extraction
- Vantage currently has 6 super critical CO2 extraction units, each with dual extraction tubes and capable of holding 4 – 5kg of biomass per extraction tube.
- These dual extraction tubes allow for one tube to be loaded while the other is being processed, increasing extraction efficiency
- These units are capable of processing a total of 1 ton of biomass per day
World Class Facility
Vantage Hemp is an American cannabidiol manufacturer based in Greeley, Colorado. Our custom-built pharmaceutical grade extraction and cannabidiol manufacturing facilities, named Falcon and Raven, deliver 62,000 sq ft of cGMP certified hemp processing including:
Extraction Capacity (kg/year)
- CBD Distillate 100,000
- CBD Isolate 50,000
Manufacturing capacity (units/year)
- SoftGel capsules – 50M+
- Tinctures – 1M
Operating Regions
- North America
- Latin America
- APAC
- European Union
Products & Services (cGMP)
- DMF – CBD Isolate (#037784)
- DMF – CBD Distillate (#036876)
- CBD and CBG Isolate
- CBD and CBG Distillate (including T-Free)
- Full Spectrum and Crude Oils
- Contract Manufacturing – Tinctures, SoftGels, Topicals, Gummies
- Clinical Trial Program Support
- R&D and Formulation Services
